2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Estrogen Receptor/ERR
  5. Estrogen Receptor/ERR Ligand

Estrogen Receptor/ERR Ligand

Estrogen Receptor/ERR Isoform Comparison

Estrogen Receptor/ERR Ligands (6):

Cat. No. Product Name Effect Purity
  • HY-107245
    Segetalin B
    		Ligand 99.51%
    Segetalin B, an orally active cyclopentapeptide found in Vaccaria segetalis, possesses estrogen-like activity. Segetalin B promotes mineralization of ovariectomized rat-derived bone marrow mesenchymal stem cells (BMSCs) in vitro and increases the level of osteocalcin, BMP-2, ALP, and SIRT1 activity. Segetalin B is promising for research of post-menopausal osteoporosis (PMOP).
  • HY-163467
    CHEMBL4224880
    		Ligand
    CHEMBL4224880 is an estrogen receptor-α (ER-α) binder.
  • HY-170334
    ER ligand-7
    		Ligand
    ER ligand-7 is the ligand for estrogen receptor, and can be used for synthesis of PROTAC ER Degrader-15 (HY-170332) as ligand for target protein.
  • HY-170339
    ER ligand-5
    		Ligand
    ER ligand-5 is the ligand for estrogen receptor, that can be used as ligand for target protein for PROTAC synthesis of PROTAC ERα Degrader-10 (HY-170336).
  • HY-W615671
    4,4'-(Cyclohexylidenemethylene)diphenol
    		Ligand
    4,4'-(Cyclohexylidenemethylene)diphenol (Compound 2) is a symmetric cyclic nonsteroidal estrogen. 4,4'-(Cyclohexylidenemethylene)diphenol has high binding affinity for estrogen receptors ERα and ERβ.
  • HY-49537
    ER ligand-10
    		Ligand
    ER ligand-10 (Compound 11a) is a weak ERa and ERβ ligand, and shows weak estrogenic activity.